Tenvir EM (Emtricitabine and Tenofovir Disoproxil Fumarate)

Tenvir EM (Emtricitabine and Tenofovir Disoproxil Fumarate)

Active ingredient: Emtricitabine / Tenofovir
Product Code: PR18898
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Tenvir-EM (Cipla) 30 tabs bottle 200 mg/ 300 mg

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30 tablets
$89.00 USD
$2.97 USD
$0.67 USD
60 tablets
$179.00 USD
$2.98 USD
$0.33 USD
90 tablets
$269.00 USD
$2.99 USD
$0.00 USD

Description

Tenvir-EM (Emtricitabine / Tenofovir)

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About Tenvir-EM

Tenvir EM Tablets are highly recommended as a Pre-Exposure Prophylaxis for the management of HIV infection. It is also used in the treatment of HIV infection. It belongs to the group of drugs called NRTI or nucleoside reverse transcriptase inhibitors. Tenvir EM is a combination of two anti-HIV medications: Emtricitabine (200 mg) and Tenofovir Disoproxil Fumarate (300 mg). It works by filtering out the Human Immunodeficiency Virus from the blood. It prevents the multiplication of the HIV thereby reducing the viral load in the body. These compounds also increase the CD4 cell count thereby supporting the body’s natural defenses against infective pathogens.

When is Tenvir EM prescribed?

Tenvir EM is primarily used for the treatment of HIV infection. It is also indicated for pre-exposure prophylaxis (PrEP) in combination with the safe sex practices to prevent the risk of sexually acquired HIV-1 in the adults who are at a higher risk. The indications for the use of this drug for PrEP are based on the clinical trials conducted in the high-risk group of men such as:
• Has a partner(s) detected with an HIV-1 infection
• Engages in a sexual activity within the higher prevalence area or social network together with at least one criterion of the following: o Absence of or inconsistent use of condoms o Diagnosis of other sexually transmitted infections o An exchange of sex for commodities like money, drugs, food, or shelter o The use of illicit recreational drugs and alcohol dependence o Incarceration PrEP is also recommended for the injection drug users including:
• An HIV-positive injecting partner
• Recurrent sharing of injection equipment It is important to note that if the clinical symptoms of HIV consistent with an acute infection are present and when the recent exposure within a month prior is suspected, patients should delay the PrEP by at least one month. They should reconfirm their HIV-1 status and/or undergo a test for the diagnosis of HIV-1 infection before beginning the use of Tenvir EM as PrEP in these cases.

Clinical eligibility for the use of Tenvir EM for PrEP:
• Documented negative HIV test result before prescribing PrEP
• No signs and symptoms of acute HIV infection

• Normal renal functions

• Absence of usage of contraindicated medications that can cause drug interactions

• Documented vaccination and hepatitis B virus infection status Other than this, Tenvir EM It may also be used to control the manifestation of other viral infections such as hepatitis B. The antiviral properties of the compounds, Emtricitabine and Tenofovir Disoproxil Fumarate, provide relief from the symptoms of the infections by inhibiting their multiplication and reducing the viral overload.


How to use Tenvir EM?

The recommended dosage of Tenvir EM in the management of HIV infection and hepatitis B depends on the severity and duration of the symptoms. The dose may have to be varied based on the CD4 count of the patient. For the prevention of HIV, a treatment with Tenvir EM may be started within 72 hours of the exposure to the virus. The doses should preferably be taken with food as this can help to increase the absorption of the medication into the body and thus, enhance its effectiveness. The doses should be taken at the same time every day. Care should be taken to avoid missing the doses as interruptions in the treatment may reduce the effectiveness of the medication. Patients are advised to consult a physician to find the best dose of Tenvir EM suitable for their specific medical condition.

 

How To use Tenvir EM for PrEP?

Tenvir EM dosage for PrEP Tenvir EM for PrEP should be taken on a daily basis in order to derive protection against HIV infection. The daily doses are best taken at the same time every day for an optimum effectiveness of the medication. Tenvir EM may also be used in two alternative ways as described below:
• Reduced dosing: This form of dosage schedule involves taking the PrEP regularly, but with a different schedule. For example, instead of a daily dose, patients can take it every other day, or four times per week.
• Event-based dosing: This form of PrEP involves taking the medication before you are planning to have sex. However, there are advantages and disadvantages of both these approaches. Patients are advised to consult a physician to determine the best dosage regimen depending on their individual circumstances. Regular monitoring is important while using Tenvir EM for PrEP. Patients are advised to undergo the following assessments tests once in every three to four months:
• 4th-generation blood test for HIV to detect the p24 antigen and antibodies
• Kidney function tests to detect the presence of proteins in urine
• Other sexually transmitted infections Patients should also undergo the yearly tests including:
• Kidney function tests for eGFR and creatinine to assess the proper functioning of the excretory system

 

What are the side effects of Tenvir EM?

The common side effects of Tenvir EM include:

• Fatigue
• Headache
• Weakness
• Nausea
• Muscle pain
• Diarrhea
• Depression
• Dizziness

 

Key highlights of Tenvir EM

• Do not use Tenvir EM, if you are allergic to Emtricitabine and Tenofovir Disoproxil Fumarate.
• Inform the physician if you are pregnant or planning to conceive before starting the treatment with this medicine.
• Breastfeeding women should exercise caution while using Tenvir EM as the effect of this drug on the infant is not fully known.
• Patients suffering from lactic acidosis, or any hepatic disorder should refrain from using Tenvir EM.
• Tenvir EM may cause dizziness and reduce the level of alertness. Hence, patients should be careful while driving or working on heavy machinery to prevent the risk of accidents.

 

What are the substitutes of Tenvir EM?

• Ricovir-EM
• Tenof EM
• Tavin EM • Truvada

 

What are the drug interactions of Tenvir EM?

Patients should inform the physician if they are using any other medication as Tenvir EM may cause drug interactions when used simultaneously with other drugs.

 

Storage

Tenvir EM tablets should be stored at a cool and dry place. It should be kept out of reach of children.

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