Seroflo Rotacap (Fluticasone + Salmeterol)

What is Seroflo Rotacap?

Seroflo Rotacap contains fine dry powdered medicine in a capsule which is meant to be inhaled using a rotahaler. It contains a combination of Salmeterol and Fluticasone. It is used to dilate constricted airways which occur in bronchoconstrictive diseases like asthma, COPD and exercise-induced asthma.

Class and Mechanism of Action

Salmeterol is a bronchodilator belonging to the group of beta2-adrenergic agonists. It stimulates an enzyme called intracellular adenyl cyclase which increases the conversion of cyclic AMP. Increased cAMP inhibits the mast cell mediators thus reducing inflammation. It relaxes the smooth muscles in the bronchial wall and allows dilation of the air passages.

Fluticasone is a corticosteroid and inhibits the inflammatory reaction by blocking the synthesis and release of inflammatory substances.

Looking after Seroflo Rotacap

Store it in a cool and dry place away from the reach of children. Clean your rotahaler after every 2 weeks.

How to take Seroflo Rotacap?

Inhale the rotacaps through rotahaler as advised. Do not swallow or chew.

Dosage

Consult your doctor for the dose.

Overdose

Consult your doctor right away.

Missed Dose

If it is time for your next dose, then skip the missed dose or else take it as soon as you remember. Do not double dose.

Warnings and Precautions

Use with caution in cases of cardiac rhythm anomalies, bone density issues, diabetes, thyrotoxicosis, tuberculosis and hypokalaemia. Do not stop treatment suddenly. It needs titrated withdrawal. Monitor blood bone mineral levels regularly.

Possible Side Effects

• Throat irritation
• Candida infection (Mouth and throat)
• Hoarseness of voice
• Upper or lower respiratory tract infections
• Headache
• Muscle cramps
• Tachycardia
• Agitation, nervousness
• Dry mouth or throat 

When should Seroflo Rotacap not be used?

Active infections, tuberculosis, status asthmaticus, children under 12 years of age, hypersensitivity to the drug

How long should you take Seroflo Rotacap?

As long as prescribed